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Exp:
Virginia’s GOP lt. governor won’t back Trump in 2024: ‘I just couldn’t’
Quote:
Virginia Lt. Gov. Winsome Sears (R) said on Thursday that she would not support former President Trump running again for the White House if he declares his candidacy, as he is expected to do next week.
Sears told Fox News’s Neil Cavuto that Trump had numerous accomplishments with the economy and with public safety, but she said voters showed in the midterm elections that they want the Republican Party to have a different leader.
Quote:
“A true leader understands when they have become a liability,” Sears said. “A true leader understands that it’s time to step off the stage, and the voters have given us that very clear message.”
She said voters are saying “enough is enough” and that America is “the prize.”
The house could still go to the democrats. I never really had a problem with Manchin. I think he genuinely represented what was best for his state, and if he didn't, it would be a republican. I had a much bigger problem with whatever craziness or corruptness motivated Sinema.
Manchin was a centrist and pragmatist , left of that hate him for not rolling over in the AOC craze 2 years ago. Kinda like the hate Republicans get for rolling over for Trump. Manchin did Dems a favor by moderating them.
I get the happiness there is no red wave but seeing as the Republicans are flat out nuts the Dems losing the House is a wake up. Need to moderate and tuck the left flanks away if they want to win the next election.
Manchin was a centrist and pragmatist , left of that hate him for not rolling over in the AOC craze 2 years ago. Kinda like the hate Republicans get for rolling over for Trump. Manchin did Dems a favor by moderating them.
I get the happiness there is no red wave but seeing as the Republicans are flat out nuts the Dems losing the House is a wake up. Need to moderate and tuck the left flanks away if they want to win the next election.
Isn't this one of the best results ever for the party in power during midterms? If anything it seems like a wake up call for the republican party.
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Isn't this one of the best results ever for the party in power during midterms? If anything it seems like a wake up call for the republican party.
If you are a non-maga republican this is probably the best outcome for you.
McConnell is in the hot seat because he spent 30milloon getting JD Vance elected and might not have needed when his PAC could have used the money elsewhere.
That the places where progressives make it through the primaries are Democrat strongholds?
John Fetterman is extremely progressive.
Pennsylvania isn't what I'd call a "Democrat stronghold" given that we just this midterm got a Dem majority in the state house (though part of that was fixing GOP gerrymandering) and PA broke for Trump in 2016. Even my home county, Allegheny, which houses Pittsburgh, isn't what I'd call "progressive."
Until about 11pm Tuesday night I was convinced Oz was going to win because I know Pennsylvania's history. I was a little less worried about Shapiro/Mastriano - no one seemed to like Mastriano outside of the extreme MAGA types, which is why it wasn't entirely shocking that Shapiro wiped the floor with him.
I think it's just that policies that we deem "progressive" in this country: healthcare for all, fair wages, maternity leave, protecting women's rights, legalizing marijuana, reasonable gun control measures, etc. are all very popular policies if you peel away the red/blue labels.
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You want a really cool under-the-radar upset? It looks like Marie Gluesenkamp Perez (D) is about to win the WA-03 seat. It hasn't been called yet and there's some way to go, but it's looking increasingly likely that she might take this seat from the Republicans. It's a rural, red district where, since redistricting in 2010, Republicans have won easily in every election. It's an R +9 seat, as per 538.
This is, of course, Jamie Herrera Beutler's seat. She was one of the ten Republicans who dared to vote to impeach the orange overlord and one who supported the January 6 commission, and so of course MAGA primaried her. She narrowly lost the primary to MAGA choice Joe Kent, who has been endorsed by Trump, Gaetz, Flynn, Gosar and friends ... that's really all you need to know about him.
Well, they seat might instead go to a young, working-class auto shop owner, who doesn't take money from corporate PACs, who wasn't heavily supported by the party and who focused on a well-run grassroots campaign. The latest numbers suggest Gluesenkamp Perez is leading Kent by 2.3 points, and the outstanding ballots might give her enough edge to pull it off.
Pennsylvania isn't what I'd call a "Democrat stronghold" given that we just this midterm got a Dem majority in the state house (though part of that was fixing GOP gerrymandering) and PA broke for Trump in 2016. Even my home county, Allegheny, which houses Pittsburgh, isn't what I'd call "progressive."
Until about 11pm Tuesday night I was convinced Oz was going to win because I know Pennsylvania's history. I was a little less worried about Shapiro/Mastriano - no one seemed to like Mastriano outside of the extreme MAGA types, which is why it wasn't entirely shocking that Shapiro wiped the floor with him.
I think it's just that policies that we deem "progressive" in this country: healthcare for all, fair wages, maternity leave, protecting women's rights, legalizing marijuana, reasonable gun control measures, etc. are all very popular policies if you peel away the red/blue labels.
I think fetterman shows a path for progressives. You can win with progressive ideas if you don't get dragged into unpopular/no win battles. If you point your message to 'helping the little guy, rural or urban, the worker' and stay away from purity tests battles that annoy the centrists... You can win.
You want a really cool under-the-radar upset? It looks like Marie Gluesenkamp Perez (D) is about to win the WA-03 seat. It hasn't been called yet and there's some way to go, but it's looking increasingly likely that she might take this seat from the Republicans. It's a rural, red district where, since redistricting in 2010, Republicans have won easily in every election. It's an R +9 seat, as per 538.
This is, of course, Jamie Herrera Beutler's seat. She was one of the ten Republicans who dared to vote to impeach the orange overlord and one who supported the January 6 commission, and so of course MAGA primaried her. She narrowly lost the primary to MAGA choice Joe Kent, who has been endorsed by Trump, Gaetz, Flynn, Gosar and friends ... that's really all you need to know about him.
Well, they seat might instead go to a young, working-class auto shop owner, who doesn't take money from corporate PACs, who wasn't heavily supported by the party and who focused on a well-run grassroots campaign. The latest numbers suggest Gluesenkamp Perez is leading Kent by 2.3 points, and the outstanding ballots might give her enough edge to pull it off.
I just saw the below video explaining the risk the Democrats took when they re-districted the lines earlier this year in Nevada by gerrymandering for a larger area that was a bit of a high risk, high reward move.
Nevada is still counting so it'll be interesting to see if the Dems risk pays off.
The insulin cost thing is like other things. It's nuanced. The average cost of insulin means almost nothing as different people use different insulin.
Quick overview:
Your body controls insulin based on a feedback system where as sugars rise it pumps out more. There's always some insulin even when sugars are low, as it's what allows cells to take in sugars and use them.When you eat, your sugars would rise so insulin levels spike after you eat.
For type 1 diabetics, they don't make insulin anymore as their body has destroyed the cells that make insulin. It would seem simple then to just inject normal insulin when you eat and you're all good. Except it doesn't work that way really. Homologous human insulin when in solution forms fairly stable hexamers that dissociate slowly. That means when you inject the insulin it takes 1-1.5 hours to hit its peak and it lasts 3 to 5 hours. That isn't ideal because your sugars spike about 15 minutes after you eat and then fall relatively fast. Therefore, using normal insulin can lead to highs right after eating and dangerous lows hours later. It also doesn't solve the basal insulin problem as you need a small amount all the time. Early insulin users would use Toronto insulin (aka normal human insulin) and NPH (additive to make it last 8-16 hours). These people had to make sure they ate at regular intervals and had lots of troubles getting their overall sugars down despite having frequent severe lows.
Science has fixed a lot of this by altering the insulin protein slightly. As insulin is a protein, it's essentially a chain of amino acids. By changing the very last amino acid they can make it dissociate much quicker or more slowly depending on what you need to do. For mealtime insulin you can make it not form the hexamers and it can peak in 15 to 30 minutes and fall within a couple hours like normal insulin. You can also make it dissociate much more slowly and have almost no peak for 24 hours for the basal insulin.
All these different insulins have different costs as some have patents and some don't. That's why using "average price across all insulin types" isn't that helpful. Toronto insulin (normal homologous human insulin) is about $30 here in Canada and I think similar in the states. NovoRapid (fast acting mealtime insulin) here in Canada is about $60-70 a vial I think (not at work, could be wrong) but is as much as $700 in the US for most people. That's largely because of all the middlemen PBMs and insurance companies. You can get the generic at Walmart for $70, but it's not likely covered by your insurance then. Here in Canada there's now biosimilars (essentially generics) that are even cheaper.
I guess what I'm saying is that yes it's more expensive in the US than Canada, that much is obvious. But saying $6 in Australia vs $12 in Canada isn't a useful comparison because we have no idea which insulins they're comparing and no idea what government subsidies/public paying, etc is involved.
Last edited by Street Pharmacist; 11-12-2022 at 11:02 AM.
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