Coronavirus News only thread

[Cali Panthers Fan]

Early returns on the trials of Remdesivir produce clear benefits for patients. The study had over 1000 participants in a randomized controlled trial.

https://www.sciencedaily.com/release...0429141311.htm

Preliminary results indicate that patients who received remdesivir had a 31% faster time to recovery than those who received placebo (p<0.001). Specifically, the median time to recovery was 11 days for patients treated with remdesivir compared with 15 days for those who received placebo. Results also suggested a survival benefit, with a mortality rate of 8.0% for the group receiving remdesivir versus 11.6% for the placebo group (p=0.059).

This is good news for severe cases requiring hospitalization as time to recovery and mortality rate drop by about 30% each. This isn't going to save everyone, but at the very least this puts a lower strain on the hospital system to care for these patients with less time spent in a bed. More complete trials are going to be coming soon, so stay tuned. Plans are to ramp up production of the drug should it be approved for use.

[EldrickOnIce]

The race for coronavirus vaccines: a graphical guide

Eight ways in which scientists hope to provide immunity to SARS-CoV-2

https://www.nature.com/articles/d41586-020-01221-y

[Street Pharmacist]

Originally Posted by Cali Panthers Fan

Early returns on the trials of Remdesivir produce clear benefits for patients. The study had over 1000 participants in a randomized controlled trial.

https://www.sciencedaily.com/release...0429141311.htm



This is good news for severe cases requiring hospitalization as time to recovery and mortality rate drop by about 30% each. This isn't going to save everyone, but at the very least this puts a lower strain on the hospital system to care for these patients with less time spent in a bed. More complete trials are going to be coming soon, so stay tuned. Plans are to ramp up production of the drug should it be approved for use.

I'm not so sure. Lots of shenanigans here. Lancet trial showed no mortality benefit, so suddenly the NIAID study changes end points for the trial to ignore mortality.

Mortality benefit did not reach significance.

Good summary by evidence here:


https://twitter.com/MarkHoofnagle/st...015063042?s=20

[Faust]

Doctors keep discovering new ways the coronavirus attacks the body:

https://www.washingtonpost.com/healt...s/?arc404=true

[DeluxeMoustache]

In case anyone is interested, the East Virginia Med School has a link to the management protocol for COVID 19

https://www.evms.edu/media/evms_publ...ol-Summary.pdf

Generally you see a suggestion that the following can help with general prevention, despite limited data: Vitamin C, Vitamin D, Zinc and Melatonin as well as Quercetin (which you can get as a supplement and is apparently found in kale, berries and red wine)

Beyond that they itemize current medications based on severity and symptoms

Found it interesting

[blankall]

https://www.ctvnews.ca/health/corona...tudy-1.4943895

Sars antibodies blocking Covid-19 virus is very good news IMO. Seems to suggest that the virus doesn't mutate quickly, when it comes to the anti-body reacting proteins, and also that exposure will likely lead to broad based immunity.

[marsplasticeraser]

With any new disease, the best strategy is to delay getting Covid as long as possible.

First of all, there are constant improvements in how to treat the disease, including drug therapies and vaccines.

Secondly, we are still learning about the disease, and it could end up being better or worse then initially feared. If it's less virulent, then that's fine, no big deal. If it is worse (and with Covid-19, there seem to be increasing long-term issues), then by delaying you can more accurately assess the risk.

I had several friends say they wanted to get Covid in the spring, as it was just a bad flu. That was a bad take then, and looking worse now.

Originally Posted by Faust

Doctors keep discovering new ways the coronavirus attacks the body:

https://www.washingtonpost.com/healt...s/?arc404=true

[DeluxeMoustache]

https://www.nytimes.com/2020/08/11/h...s-indoors.html

Researchers have been able to confirm that virus can be aerosolized and have succeeded in capturing viable samples

It has been hypothesized and expected, but the challenge of collecting virus from the air without damaging it has been a challenge. I believe they introduced pure water vapour and captured virus in the condensation

A research team at the University of Florida succeeded in isolating live virus from aerosols collected at a distance of seven to 16 feet from patients hospitalized with Covid-19 — farther than the six feet recommended in social distancing guidelines.

Link to the scientific publication:

https://www.medrxiv.org/content/10.1....03.20167395v1

[Ashasx]

nm

[Domoic]

Pfizer's COVID vaccine approved today for emergency use in Canada.

Reminder --- Pfizer Canada and BioNTech will supply the Government of Canada a minimum of 20M doses (and up to 76M doses) of the vaccine through 2021.

[edslunch]

Originally Posted by Domoic

Pfizer's COVID vaccine approved today for emergency use in Canada.

Reminder --- Pfizer Canada and BioNTech will supply the Government of Canada a minimum of 20M doses (and up to 76M doses) of the vaccine through 2021.

First injections next week! I guess we’re not as screwed as feared