[News] NHL suspends Leafs forward Carter Ashton 20 games for PEDs

[landshark]

Originally Posted by zyzz

Clen is hardly an enhancing drug. It's used for cutting weight and that's it, Using this stuff while doing cardo or any sort of sport would be asking for a heart attack. Learn some facts before you type.

That may be the line your gym buddies are telling you, but it has little to do with actual facts.

http://en.wikipedia.org/wiki/Clenbuterol

Clenbuterol, marketed as Dilaterol, Spiropent, Ventipulmin, and also generically as clenbuterol, is a sympathomimetic amine used by sufferers of breathing disorders as a decongestant and bronchodilator. People with chronic breathing disorders such as asthma use this as a bronchodilator to make breathing easier. It is most commonly available as the hydrochloride salt, clenbuterol hydrochloride.

Clenbuterol is a β2 agonist with some structural and pharmacological similarities to epinephrine and salbutamol, but its effects are more potent and longer-lasting as a stimulant and thermogenic drug. It causes an increase in aerobic capacity, central nervous system stimulation, blood pressure, and oxygen transportation. It increases the rate at which body fat is metabolized while increasing the body's BMR. It is commonly used for smooth muscle-relaxant properties as a bronchodilator and tocolytic.

[Mickey76]

I am surprised whenever I read a thread like this at the moral grandstanding that goes on. People are shocked and disgusted and would never do such a despicable and horrible thing as use an inhaler to enhance their performance. If using an inhaler would get or keep me in NHL I would have them delivered by the truckload.

[zyzz]

Originally Posted by landshark

That may be the line your gym buddies are telling you, but it has little to do with actual facts.

http://en.wikipedia.org/wiki/Clenbuterol

Clenbuterol, marketed as Dilaterol, Spiropent, Ventipulmin, and also generically as clenbuterol, is a sympathomimetic amine used by sufferers of breathing disorders as a decongestant and bronchodilator. People with chronic breathing disorders such as asthma use this as a bronchodilator to make breathing easier. It is most commonly available as the hydrochloride salt, clenbuterol hydrochloride.

Clenbuterol is a β2 agonist with some structural and pharmacological similarities to epinephrine and salbutamol, but its effects are more potent and longer-lasting as a stimulant and thermogenic drug. It causes an increase in aerobic capacity, central nervous system stimulation, blood pressure, and oxygen transportation. It increases the rate at which body fat is metabolized while increasing the body's BMR. It is commonly used for smooth muscle-relaxant properties as a bronchodilator and tocolytic.

Nice copy and paste job. Try running 100mcg of clen and playing a high intensity sport.

[driveway]

Clenbuterol is not approved for human use in either Canada or the U.S.—so that inhaler either came from Europe or was designed for horses. But it is one of the most popular banned weight-loss drugs, one that's popped up again and again in boxing, cycling, and baseball. It's huge among bodybuilders looking to get cut, and is on the blacklist of the IOC and every major sports league.

Deadspin.

[ExiledFlamesFan]

I work with asthmatics everyday and I have never actually heard of this drug until now. Thanks to driveway for some more info.

It's half life is insane, 36-48 hrs compared to less than 2 hrs for Ventolin. Sounds like it's a stimulant.

[Hackey]

Originally Posted by Mickey76

I am surprised whenever I read a thread like this at the moral grandstanding that goes on. People are shocked and disgusted and would never do such a despicable and horrible thing as use an inhaler to enhance their performance. If using an inhaler would get or keep me in NHL I would have them delivered by the truckload.

Exactly. Guy took something that allowed him to barely crack an NHL roster. Rules are rules so he's only got himself to blame and as a result has to pay the price. Big deal though. It's just sports and the advantage is obviously minimal. I feel more offended that he lied than the actual use of the drugs.

[Buck Murdock]

Originally Posted by zyzz

Nice copy and paste job. Try running 100mcg of clen and playing a high intensity sport.

Sounds like you're talking about bodybuilding. Back in the day I saw guys take this and it certainly helped their performances. Made them feel like they were going to have a heart attack, but it certainly had an effect beyond "weight cutting".

[Hugh Jahrmes]

I know a ton of waitresses who always talk about taking it, jittery as hell discussing how pretty it would make them.

I used to work out fairly heavily and was offered it for cutting a handful of times. One time I tried two drops of the liquid suspended stuff, and can honestly say I would never consider mixing it with high intensity sports. Very uncomfortable feeling.

[Nage Waza]

Originally Posted by zyzz

Clen is hardly an enhancing drug. It's used for cutting weight and that's it, Using this stuff while doing cardo or any sort of sport would be asking for a heart attack. Learn some facts before you type.

Perhaps you should be reading up on it.

It is absolutely a performance enhancing drug. Want to drop pounds while building muscle? This is what you take.

This 'increases performance' in the gym.

It absolutely works and allows people to work out (extra) while burning fat and keeping their muscles.

[cral12]

Originally Posted by Street Pharmacist

Yeah. Not sure how much benefit clenbuterol would provide. It's basically ventolin with a longer half life. In really high doses I suppose it might get you up for a game, but so could coffee.

I don't know much about the doping uses of it, but I do know is not readily commercially available in Canada, and highly doubt it is in the states. Seems extremely weird sometime would just randomly have an clenbuterol inhaler that for asthma. Salbutamol (or Albuterol as it's called down south) is what EVERY doctor prescribed. Something is weird here

Agree.

I'm also a pharmacist by day (draft junkie as alter ego)...

Anyway, this is absolutely absurd. I actually liked the kid as prospect, but this is a pretty pathetic excuse. NO ONE in North America is prescribed "clen" for asthma, and his "gym buddy" obviously obtained it through dubious mean. If you're going to be a pro player, act like a pro. How could you NOT be careful about anything you ingest.

The use of "clen" is widespread in the world of cycling.

I'll have to pull the full article at work, but found this after a quick search:

"Clenbuterol Impairs Muscle Quality and is Potentially Dangerous

Dirk Habedank, MD et al
Published Online: June 26, 2008
DOI: http://dx.doi.org/10.1016/j.healun.2008.05.002
Abstract

In their study, Kamalakkannan et al1 investigated the effect of an anabolic agent on muscle strength and exercise capacity in patients with chronic heart failure (CHF). Their investigation of clenbuterol is of great interest and complements an earlier study by Harrington et al,2 who used salbutamol in the treatment of CHF and showed a potential negative effect of this β2-agonist. Harrington et al found that salbutamol failed to improve exercise capacity and increased the risk of arrhythmia, and therefore they proposed a trial with clenbuterol as a more potent anabolic agent."

[cral12]

Aside: His agent not the most savvy either - if he truly wanted to lay doubt he should've pleaded food contamination as the culprit. A quick search revealed 2 articles highlighting where this took place, albeit in other parts of the world.

[sureLoss]

^
Not saying that I necessarily believe his story about the borrowed inhaler, quite possible the guy he supposedly got the inhaler from was a euro.

Is the drug prescribed in Europe as Asthma medication?

[Street Pharmacist]

Originally Posted by sureLoss

^
Not saying that I necessarily believe his story about the borrowed inhaler, quite possible the guy he supposedly got the inhaler from was a euro.

Is the drug prescribed in Europe as Asthma medication?

I highly doubt it. It's old and much riskier because of it's long half life.

Martindale's only lists single ingredient products for Austria, Czech Republic, Germany, Greece and Italy (and a few non European countries). Multiple ingredients in Austria and Germany.

Even then, I highly doubt your average doctor prescribes it as salbutamol would very likely be available everywhere

[Buck Murdock]

Originally Posted by Street Pharmacist

I highly doubt it. It's old and much riskier because of it's long half life.

Martindale's only lists single ingredient products for Austria, Czech Republic, Germany, Greece and Italy (and a few non European countries). Multiple ingredients in Austria and Germany.

Even then, I highly doubt your average doctor prescribes it as salbutamol would very likely be available everywhere

With this in mind, would it be unlikely that the drug got into his system via inhaler? I assume there are other ways to get clenbuterol into your system. Also, I assume the amount of the drug found in his system would confirm inadvertent use vs premeditated cheating?

[Street Pharmacist]

Originally Posted by Buck Murdock

With this in mind, would it be unlikely that the drug got into his system via inhaler? I assume there are other ways to get clenbuterol into your system. Also, I assume the amount of the drug found in his system would confirm inadvertent use vs premeditated cheating?

I do doubt it was via inhaler. A quick google search suggests tablets are readily available on the black market. Again, I don't know what's available elsewhere, but I'd be quite shocked to see someone on a clenbuterol inhaler for asthma in a first world country.

It would depend on the assay used in the test. Typically (to my knowledge), the results come back either positive or negative based on a minimum threshold. Example hypothetical: let's say a regular poppy seed contains an incredibly minute amount of morphine and summertime eats a poppy seed muffin. The drug tests threshold would have to be set at a level to determine guilt, not just whether the substance is in the blood, so it would not be a positive for morphine in this case. Urinalysis is even trickier. This may not be how it works for athlete testing though.


Edit: from WADA

Clenbuterol is a prohibited substance and there is no threshold under which this substance is not prohibited.

At present, and based on expert opinions, there is no plan to introduce a threshold level for clenbuterol.

It is possible that under certain circumstance the presence of a low level of clenbuterol in an athlete sample can be the result of food contamination. However, each case is different and all elements need to be taken into account, along with the context of the case.

[driveway]

From doing some googling, the only European country I can find who may actually produce a Clenbuterol-containing inhaler is Bulgaria. The Czech Republic, Austria, and Germany do prescribe a Clenbuterol medication, brand name Spiropent, but it comes in tablet form.

[GioforPM]

Originally Posted by driveway

From doing some googling, the only European country I can find who may actually produce a Clenbuterol-containing inhaler is Bulgaria. The Czech Republic, Austria, and Germany do prescribe a Clenbuterol medication, brand name Spiropent, but it comes in tablet form.

No one from Bulgaria would ever abuse PEDs.

[combustiblefuel]

I almost believed him . until I looked into the drug.

I almost believed him that he had to borrow an inhaler because of an attack because this has happened to my girlfriend. She was working an had an attack, she had forgot her inhaler at home. I got a call at home saying she needed me to bring it asap. Before I was even out the door at home . I received another call saying a tourist had noticed she was having a severe asthma attack and immediately handed her there inhaler.