Okami is coming out for Wii next spring, which is wicked because I've been searching for a copy of the PS2 one for a while now, but with no avail. It'll be an exact port of the PS2 one which if fine by me because I've never played the original. Plus the Wiimote seems to make perfect sense as the brush rather than the dual analog controls.
I may also go out and buy Mercury Meltdown, since it got a good rating at Gamespot, and is only $20. Zak and Wiki also got a good review, and is only $40 I think. I don't think I can bring myself to buy it though.
Other games being released soon that look like they have merit:
RE4: Umbrella Chronicles
Ghost Squad (on the rails shooter)
Medal of Honor Heroes (32-person online multiplayer, no friend codes required!)
Mario Galaxy
Manhunt 2
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