Yeah, I've been closing out of Chrome and then re-opening, which temporarily fixes it. But it's cropped up again very quickly each time. I think it's related to the DirectWrite settings, which were discussed
here. I've "diasbled" the Disable DirectWrite option (that's not intuitive!) now, and things seem to be OK now.
EDIT: I enabled this again, as DirectWrite was making other sites I visit just as messed up.