I'm in fantasy leagues with a bunch of regular guys and I've done the baseball pools primarily so I know when the football pool will be. Most years I do a bit of tinkering here and there with the team but this year I left the Yahoo draft order alone, used the autodraft, looked at my team maybe once every couple months if that and magically ended up in 2nd place. So as Kriz says, luck has a ton to do with it.
Like any sport the specialty positions are important. Depending on your setup pitchers could be the specialty position. Also I've found it's handy to have players with multi-positional status so you have more latitude to move guys around for the inevitable injuries and slumps.
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