I few months ago I read the "The Incal", which has a reputation as one of the all time best graphic novels. It's one of the premier works by artist Moebius and its kind of a mash up of Heavy Metal and Dune. Apparently it started as storyboards for a Dune movie that ended up being scrapped, so the artist/writer decided to make their own story based on those storyboards.
The story itself is bat#### crazy, it's filled with aliens, mutants, rebellions, techno-popes, buddhist meditation, male&female Siamese-twin space-emperor, it's got it all. The whole thing feels like a ramshackle mess that could fall apart at any time, but ends up being a really unique story that lives up to it's status as one of the all time best graphic novels. I think it's a must-read for anyone who's a fan of the medium, but might be too weird for the casual crowd.
img spoilered for size.