I still have a 27" monitor so I can't really comment on usability, but to me $1100 for a 49" isn't all that staggering in terms of cost/benefit IMO. Less than the price of a phone.
I've always been fine with putting more money into the things I use the most to get exactly what works best for me. If I use a monitor 7.5 hours a day 5 days a week (or more) I'm fine with spending more if there's a noticeable benefit.
Get em both, try it out, return the one that doesn't feel as good.