For disturbing, 'Requiem for a Dream' gets my vote.
A great movie I'm sure not many (if any) have heard about here is called 'Samsara.' A Buddhist monk in training has to decide between his current path, and the thoughts of love (and the urges of sex). Samsara is the Buddhist term for 'the physical world'. (Loosely translated, it's really more of a philosophy than an actual word.)
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