I just finished watching an excellent Frontline World tonight (had a good expose on Canadian soldiers in Afghanistan FYI), and they profiled an organization called Kiva.
Kiva is a non-profit organization that lets you donate to micro-credit bureaus around the world and help fund small independent businesses.
For as little as $25US you can help someone around the world get a jump on a new venture to help support their family and community.
I was so blown away that I had to donate right away. I helped fun a young 23 year old man from Toga start his own barbershop.
Profile here:
http://www.kiva.org/app.php?page=bus...=about&id=5804
Each person requesting a micro-loan has a profile and image and brief description on why they would like a loan. It really brings a new humanistic aspect to donating to charities.
Kiva has a 100% repayment rate, and I think is a fantastic idea.
Have a look
http://www.kiva.org
Edit: Seeing as how the show was on Frontline, I think their site got a bit swamped. Might be a bit slow, but definitely have a look!