I guess that depends on what they define as serious. 20 per 100K doesn't sound too far out of line with other data assuming we're not talking strictly about life-threatening reactions. mRNA and viral vector vaccines unfortunately have relatively high rate of adverse reactions, which is why it's so annoying that we've basically ignored potential improvements/alternatives. Novavax (a more traditional vaccine) should absolutely be getting used more widely so we can have data on if it is better tolerated, but barely anywhere is using it.
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