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para transit fellow · 03-31-2022, 01:40 PM

I recall Bell's palsy was noticed/discussed during the first vaccine trials.

I couldn't remember the exact value from 2020 but i dug around for an article to offer some recent numbers ( instead of the half remembered figures in my head):

https://jamanetwork.com/journals/jam...rticle/2781368

Generally, The annual incidence of BP is 15 to 30 per 100,000 people. The Covid vaccine trials were finding an incidence of 19 cases per 100,000. Interesting thing was that amongst people who recovered from COVID19, the incidence seems to be 82 per 100,000

I thought this was interesting:
"The mechanism of paralysis is thought to be viral, ischemic, and/or immune mediated. The hypothetical mechanism of COVID-19 associated with BP is thought to be molecular mimicry attributable to a neuroimmunologic process between microbial and nerve antigens."

I remembered the BP phenomena because it reminded me that sometimes we have to ask the question "so what is a 'normal' incidence?"

Understandably, your literature searches may be different.

03-31-2022, 01:40 PM	#11
para transit fellow Powerplay Quarterback Join Date: Oct 2010 Exp:	I recall Bell's palsy was noticed/discussed during the first vaccine trials. I couldn't remember the exact value from 2020 but i dug around for an article to offer some recent numbers ( instead of the half remembered figures in my head): https://jamanetwork.com/journals/jam...rticle/2781368 Generally, The annual incidence of BP is 15 to 30 per 100,000 people. The Covid vaccine trials were finding an incidence of 19 cases per 100,000. Interesting thing was that amongst people who recovered from COVID19, the incidence seems to be 82 per 100,000 I thought this was interesting: "The mechanism of paralysis is thought to be viral, ischemic, and/or immune mediated. The hypothetical mechanism of COVID-19 associated with BP is thought to be molecular mimicry attributable to a neuroimmunologic process between microbial and nerve antigens." I remembered the BP phenomena because it reminded me that sometimes we have to ask the question "so what is a 'normal' incidence?" Understandably, your literature searches may be different.