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Old 10-01-2021, 05:31 PM   #390
curves2000
First Line Centre
 
Join Date: Dec 2013
Location: Calgary, Canada
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Quote:
Originally Posted by opendoor View Post
There's nothing "traditional" or "old tech" about viral vector vaccines. The first one ever released for human use was in 2019, and they still do basically the same thing as mRNA vaccines where they stimulate your body to create spike proteins, but do a less effective job of it and with more adverse reactions.

If the government is really serious about coddling peoples' fears, then they should be fast-tracking Novavax. It's far more effective than the viral vector vaccines based on trial data, has fewer adverse reactions than either mRNA or viral vector vaccines, and the technology has been in wide use for nearly 40 years with the Hepatitis B shot (and later HPV and flu shots). The amount of people who are too paranoid to take an mRNA vaccine but who will be willing to inject a technology that's just as new, but that has more safety issues is probably tiny.

And were are you getting the "through the roof" antibody response at 45 weeks for AZ? The UK is finding that effectiveness is dropping to 47% at 20 weeks and prevention of hospitalization drops to 77% at the same time:

https://www.ft.com/__origami/service...ext&width=1260

There's a reason why the UK has decided to only using mRNA vaccines for boosters.

I will be the first to say that it does appear you have a vast level of knowledge in regards to most things realted to Covid and to the vaccine development etc, I just try to follow the headlines and some of the research.

As for the J&J vaccine and the AZ, I do think the data is about as clear as it can be, they are very very very effective vaccine. They prevent death and keep people out of hospital and that is what we know. It does sound like the Premier's are trying to get some J&J doses for some reason. As for the other vaccines? I really don't know too much but is it an option for Health Canada to fast track?

As for the AZ shot, we know that the 12 week interval produced a strong level of protection across the board. In July AZ released findings showing that waiting 15-25 weeks produced an even stronger response and waiting 45+ weeks produced an antibody response 4 times that of the 12th week with immunity lasting a year.

I do know there is some disagreement between AZ and the government on the need to boost everyone else 50+. The data will be important to know.

https://www.astrazeneca.com/media-ce...hird-dose.html
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