[opendoor]

Originally Posted by New Era

Not even remotely close to being accurate. Arizona is out of vaccine right now. Not even scheduling 1st responders because there is no vaccine available and no deliveries on the horizon. If there were shipments of vaccines headed this way scheduling would continue. But scheduling is disrupted, because why? No vaccine available. Same problem exists across the country. People are lining up for their scheduled appointments then left sitting in their cars because sites are out of vaccine.

Jesus Christ man, I laid out a dozen links from across the nation that shows how dire the situation is and just how bad it is. My municipality has the infrastructure to deliver, but no vaccine is available. None. We are being told that we may not see our 1st responders vaccinated for another six to eight weeks. That is already a month behind schedule, and it is all because vaccine is not available. If you're in phase three, you're now looking at fall before you can hope for a vaccine, because there isn't any available!

Really? The Trump administration had instructed states to use all vaccine available, with no guarantee of delivery of future doses. That is irresponsible and not a proper plan to solving the problem. Let me guess, if you're on chemo its okay to skip a treatment here or there or delay your treatment? This is beyond stupid now.

The "US" might be receiving doses, which according to the feds they are not, but those are not being made available to the states, who are administering the vaccination program. If the vaccine is being received by the feds, they aren't sharing that information. If they are shipping it out, is isn't making it to the states.

If everything you're saying is true, and places are all out of vaccine and there are no deliveries on the horizon, how are there 1M+ vaccinations per day throughout the country? And how are weekly vaccinations roughly matching the number of weekly delivered doses on the CDC site I linked? That would be impossible if the doses weren't ending up in the states' hands in regular intervals.

If what you're saying is true, vaccination numbers in the coming days will drop to almost nothing, are you really expecting that to happen? Or do you think they'll stay around 1M per day or even scale up? I'd bet on the latter.

Yeah, don't try and apply the interval from AstraZeneca to Pfizer or Moderna. The difference between the two is 42 days, which is twice the longest period for the clinical on the two vaccines in use in the US. People should be getting that booster in the three to four week span like directed, otherwise they put their vaccination at risk.

The Pfizer interval in the trial was 19-42 days; if they had no problem going up to 42 days and their trial showed no difference in efficacy with those intervals, then potentially (and only potentially) extending the interval to that length in the event of supply disruptions is a completely logical thing to do. Obviously you aim for the recommended dosing interval whereever possible. And with the US's robust and predictable supply, that shouldn't be an issue even if states don't hold all of their 2nd doses in storage.

A minor correction to your claim. The variant was identified on December 14th, a week after vaccinations began, and they estimate the mutation began sometime in September. The scientists trying to solve this problem identified the risk of delaying the booster and predicted possible mutation, like the one in the UK (not the mutation itself but a similar outcome). They made those predictions based on what they saw in trials, and the UK mutation is exactly what they predicted but unrelated. The variance in vaccine makes this issue that much harder to track and control.

You're correct, I misspoke. The earliest sample that had the B.1.1.7 variant was from September so the mutation occurred prior that point, though it wasn't identified as a variant of concern until December.