[Lanny_McDonald]

Originally Posted by opendoor

Of course regular deliveries are happening. States are receiving allocations and deliveries of both vaccines every single week:

https://data.cdc.gov/Vaccinations/CO...uris/saz5-9hgg

https://data.cdc.gov/Vaccinations/CO...b7pe-5nws/data

And jurisdictions with far less regular or secure deliveries than the US are not holding back 2nd shots, so what I said was totally correct.

Not even remotely close to being accurate. Arizona is out of vaccine right now. Not even scheduling 1st responders because there is no vaccine available and no deliveries on the horizon. If there were shipments of vaccines headed this way scheduling would continue. But scheduling is disrupted, because why? No vaccine available. Same problem exists across the country. People are lining up for their scheduled appointments then left sitting in their cars because sites are out of vaccine.

At this point US production is 100% destined for the US. There are no delays while doses are shipped to other countries. The US is seeing very consistent deliveries right now and in the last 5 weeks the US has received 9.4M, 8.4M, 8.3M, 8.6M, and 8.6M doses respectively. If you can point to specific evidence of states seeing large, 1+ week gaps in deliveries I'm all ears; but I've seen no evidence of that.

Jesus Christ man, I laid out a dozen links from across the nation that shows how dire the situation is and just how bad it is. My municipality has the infrastructure to deliver, but no vaccine is available. None. We are being told that we may not see our 1st responders vaccinated for another six to eight weeks. That is already a month behind schedule, and it is all because vaccine is not available. If you're in phase three, you're now looking at fall before you can hope for a vaccine, because there isn't any available!

No one is advocating skipping the 2nd dose. However delaying a booster shot (within a reasonable time frame) has virtually no effect on long term efficacy. And for some vaccines (AstraZeneca's and some others) it has shown to be more effective than a shorter interval. Also, the CDC recommendation allows the 2nd dose up to 6 weeks later for both vaccines.

Really? The Trump administration had instructed states to use all vaccine available, with no guarantee of delivery of future doses. That is irresponsible and not a proper plan to solving the problem. Let me guess, if you're on chemo its okay to skip a treatment here or there or delay your treatment? This is beyond stupid now.

As the links above show, the US is seeing remarkably consistent deliveries from both companies. Of course they're running out of doses, everywhere is because they're getting it into peoples' arms. That's a good thing. The idea that better distribution or coordination is going to create more doses out of thin air is flatly incorrect. The bottleneck right now is manufacturing, as it is everywhere.

The "US" might be receiving doses, which according to the feds they are not, but those are not being made available to the states, who are administering the vaccination program. If the vaccine is being received by the feds, they aren't sharing that information. If they are shipping it out, is isn't making it to the states.

The Pfizer trial protocol was 19-42 days, so some participants received their 2nd dose up to 6 weeks after the first with no detected difference in efficacy between those who received their booster shot earlier or later. That's why most jurisdictions are comfortable going up to about 6 weeks for a 2nd dose where necessary. The UK is an outlier in that, but they are now primarily using the AstraZeneca vaccine where a 12-week interval proved to be more effective in the clinical trials than the protocol of 4-weeks between doses.

Yeah, don't try and apply the interval from AstraZeneca to Pfizer or Moderna. The difference between the two is 42 days, which is twice the longest period for the clinical on the two vaccines in use in the US. People should be getting that booster in the three to four week span like directed, otherwise they put their vaccination at risk.

And speaking of dangerous disinformation... the B.1.1.7 variant was identified in September, long before vaccinations started. Trying to imply that the UK delaying their 2nd doses has something to do with that variant (as you did twice in this one post) is completely false and misleading. You might want to get a better handle on this stuff before talking down to people, telling them they don't have a clue what they're talking about, and accusing them of spreading dangerous disinformation.

A minor correction to your claim. The variant was identified on December 14th, a week after vaccinations began, and they estimate the mutation began sometime in September. The scientists trying to solve this problem identified the risk of delaying the booster and predicted possible mutation, like the one in the UK (not the mutation itself but a similar outcome). They made those predictions based on what they saw in trials, and the UK mutation is exactly what they predicted but unrelated. The variance in vaccine makes this issue that much harder to track and control.