[TorqueDog]

Originally Posted by #-3

As with most dietary topics, good research is hard to find, basically because you can't depend on accurate reporting for trial subjects. So most of the studies surrounding the impacts of Ketones on health is related to type 1 diabetes.

Which as we'll soon see is the problem with your claims; you don't appear to understand the difference between nutritional ketosis and ketoacidosis as it pertains to diabetics, and are conflating the two.

Originally Posted by #-3

Basically there is a good body of evidence that high enough ketone levels in your blood is a critically dangerous condition. And a growing body of evidence that long term exposure to high levels generally just wears on your organs that control for this.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734222/

Alright, lesson one. Repeat after me: ketoacidosis is not ketosis.

Originally Posted by #-3

https://www.medicalnewstoday.com/art...80858.php#diet

Again, talking about ketoacidosis and not ketosis. Also, some of the sources from that article:

https://www.ncbi.nlm.nih.gov/pubmed/18175736

Spoiler!

RESULTS:
Ad libitum energy intakes were lower with the LC diet than with the MC diet [P=0.02; SE of the difference (SED): 0.27] at 7.25 and 7.95 MJ/d, respectively. Over the 4-wk period, hunger was significantly lower (P=0.014; SED: 1.76) and weight loss was significantly greater (P=0.006; SED: 0.62) with the LC diet (6.34 kg) than with the MC diet (4.35 kg). The LC diet induced ketosis with mean 3-hydroxybutyrate concentrations of 1.52 mmol/L in plasma (P=0.036 from baseline; SED: 0.62) and 2.99 mmol/L in urine (P<0.001 from baseline; SED: 0.36).

CONCLUSION:
In the short term, high-protein, low-carbohydrate ketogenic diets reduce hunger and lower food intake significantly more than do high-protein, medium-carbohydrate nonketogenic diets.

https://www.ncbi.nlm.nih.gov/pubmed/23801097

Spoiler!

Recent work over the last decade or so has provided evidence of the therapeutic potential of ketogenic diets in many pathological conditions, such as diabetes, polycystic ovary syndrome, acne, neurological diseases, cancer and the amelioration of respiratory and cardiovascular disease risk factors. The possibility that modifying food intake can be useful for reducing or eliminating pharmaceutical methods of treatment, which are often lifelong with significant side effects, calls for serious investigation. This review revisits the meaning of physiological ketosis in the light of this evidence and considers possible mechanisms for the therapeutic actions of the ketogenic diet on different diseases. The present review also questions whether there are still some preconceived ideas about ketogenic diets, which may be presenting unnecessary barriers to their use as therapeutic tools in the physician's hand.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251269/

Spoiler!

Besides a positive effect on weight loss, studies have shown that low-carbohydrate ketogenic diets also reduce serum triglycerides dramatically. Elevated serum triglycerides are common among Asian Indians, and this is one of the features of the so-called Asian Indian Phenotype9. Reduction in total cholesterol and increase in high-density lipoprotein cholesterol have also been reported. A key enzyme in cholesterol biosynthesis is 3-hydroxy-3-methylglutaryl-CoA reductase, which is activated by insulin. This means that an increase in blood glucose and consequently of insulin levels will lead to increased endogenous cholesterol synthesis. A reduction in dietary carbohydrate will thus have the opposite effect and this, coupled with the additional inhibition by dietary cholesterol and fats on endogenous synthesis, is likely to be the mechanism by which physiological ketosis can improve lipid profiles4.

Thus, low-carbohydrate ketogenic diets have been shown to have immense benefits in blood sugar control. There are some reported beneficial effects on cancer and neurological disorders such as Alzheimer's disease and epilepsy10 although these are not discussed further here as it is beyond the purview of this article.

However, there are also several adverse effects of ketogenic diets. These include muscle cramps, bad breath, changes in bowel habits, keto-flu and loss of energy11. Hence, monitoring individuals on keto-diet closely once or twice a month for blood glucose, ketones cardiac and other parameters is essential.

Yeah. Try again.

Originally Posted by #-3

My last claim was that you could not find a well controlled study that would show a substantial enough benefit to offset the risks of a diet like this.

Well, let's go off of one of the sources from your second link, shall we?

The benefits are weight loss, improved outcomes for / prevention of cardiovascular disease, diabetes, metabolic syndrome, PCOS, Alzheimer's, acne, cancer, ALS, and improved HDL levels.

The risks are muscle cramps (supplement with potassium), bad breath (Gum? A mint? A quick gargle with mouth wash?), changes in bowel habits (never trust a keto fart), keto-flu (goes away in two or three weeks, sooner if you've fat adapted before), loss of energy (debatable and depends heavily on the individual).

Let's just go off of the main reason people follow ketogenic diets; they're obese or overweight, and need to lose weight to improve health outcomes. Click here and scroll down to "Complications". You tell me if higher risk of heart disease and strokes, high blood pressure and abnormal cholesterol levels, type 2 diabetes, insulin resistance, cancer of the uterus, cervix, endometrium, ovary, breast, colon, rectum, esophagus, liver, gallbladder, pancreas, kidney and prostate, heartburn, gallbladder disease and liver problems, infertility and irregular periods in women, erectile dysfunction in men, sleep apnea, osteoarthritis, lower quality of life (depression, disability, sexual problems, shame and guilt, social isolation, lower work achievement)... is it worth it yet?

... nah, better not, might get muscle cramps.