Walking is definitely the best way to get around and to actually see stuff. Don't be afraid to take some side roads since they all curve anyway. You'll discover tons of cool stuff everywhere in the historic centre, and beyond if you choose to go further. Ozy's recommendation of bringing proper shoes is probably the best advice for a trip to Rome.
Buses are slow because traffic, and stuffy as hell
Metro is underground so you miss tons of cool things
Taxis will literally take you for a ride
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