Currently in Rome, I would recommend getting advanced tickets if possible for the Sistine Chapel and maybe the colosseum, but that's about it. There is lots of ruins and historic monuments that don't require lineups.
Pompeii is around Naples and not recommended to do from Rome unless you plan to do an overnight stay. Too far in a day, travel alone will be a slog.
Also, bring sunscreen. It's ####ing hot here.
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