If you have to go portable I suggest looking for a dual-hose unit. No portable will compare to central or a mini-split unit, however the dual-hose portables are more efficient and perform better overall. On the downside they tend to be pricier and there is less selection to choose from.
I've done the acrylic sheet over my casement window in the past. Works well, but make sure you have the hole placed in front of the latch - I didn't and it was a pain to close and latch the window!
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