IT guy here. I use Avast for A/V. That's all I do and I've never had an issue. Occasionally I'll run a malware scan (like once a year or maybe more) and I always come up clean. The computer is shared with my wife and three kids.
The only time I had a problem was when my nephew used the computer and wanted to put some cool minecraft mods on the computer for my kids. But I don't worry about him because he's not welcome at my house anymore (for reasons completely unrelated to malware and viruses).
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