I can't speak for the medical profession but I'm the same age as you and have recently made significant life changes including moving to a different city and starting to transition away from my current career. Its certainly a bit daunting at times but at the end of the day when you break it down its not like its life or death. We tend to magnify the risks in our own minds.
If you find its not for you in a couple of years, could you go back and do what you were already doing? I know I probably could.
Tim Ferriss talks about an exercise called fear setting. Look it up. Basically it gets you to write down all the worst case scenarios of your decision and get an understanding of their impacts on your life -- usually the impacts are not as bad as you think or at least have a solution.
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A few weeks after crashing head-first into the boards (denting his helmet and being unable to move for a little while) following a hit from behind by Bob Errey, the Calgary Flames player explains:
"I was like Christ, lying on my back, with my arms outstretched, crucified"
-- Frank Musil - Early January 1994
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