The Sanchez transfer is interesting because he plays at a position where they already have Vertonghen and Alderwielder, plus Dier can play at CB if needed and Wimmer wasn't that bad. Does make you wonder if they plan to continue their shift to a 3-4-2-1 full time this year.
Helps hide the depth issues they have at LB/RB if they are willing to play those formations more.
Kane
Alli - Eriksen
Rose - Dier - Dembele - Walker-Peters
Vertonghen - Alderweireld - Davidson
Keeps their top three together, and would be a dominant back 3 when they are together. Plus you still have Dier that can drop back and cover. Helps with some of the depth issues by moving to that formation too.
Attacking: Kane, Alli, Eriksen, Son, Jannsen, Lamela
LM: Rose, Davies, N'Koudou
CM: Dembele, Wanyama, Sissoko, Winks
RM:Walker-Peters, Trippier
CB:Vertonghen, Alderweireld, Sanchez, Carter-Vickers
Everywhere: Dier
Depth with that formation looks decent. Could use another RM but Dier can play there and Walker-Peters was impressive in Game 1. Only real hole IMO is a striker that can spell Kane, Son can do it but I'm not sure he is best suited for that role.