I did a option D without the front door and it was ok but I felt like the side driveway ate up a bit too much yard space. I don't know that it would have been any net gain moving the garage forward in the yard, but the remaining space would have been more useable. I ended up with a small chuck of yard that was too narrow for anything.
Speaking from SK, where we have moved away from rear alley garbage and the city is doing less alley maintenance, and with seemingly incresed incidents of pilfering throuhg cars in alleys, I would close off the alley and go with option C. I like A but 2 doors adds costs and doors are not as thermally efficient as walls if you're heating.
I am really getting more paranoid these days and would go for the most secure option. You can't stop all the thieving but you can make yours the least attractive on the block.