I think you can, on Glympse set it up so that the "Glympse" session between people is permanent. It's a roundabout way of doing it, but I had something like that with my wife before we both got iPhones.
I looked at the auto reply, but it doesn't seem to include special messages kind of a "I am driving, blah blah blah" response.
I would keep search in the App Store. I would expect that somebody else with app programmming abilities has done something already.
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