[Harry Lime]

Flamesguy and Wasted Youth...

Spoiler!

I actually like the idea that she was the impetus for the super soldier program. It is coming from the opposite end of the spectrum, but fits the narrative.

The only way that the radioactive accident would work in the overarching story is if it was the same accident that blinded Murdock. That would just be too many radioactive accidents, otherwise.

In the comics, Captain America looking down on the crumpled form of Nuke, knowing that recreating the super soldier program was the reason that Nuke existed was a great moment. Sadly one that we probably won't get to see.

I agree that Kilgrave was a fantastically played villain. If he lived, DD would have been his monkey-boy assassin, though.