My brother and his wife just discovered bed bugs in their home, they were bringing home newborns and so they did not want to apply any chemical treatments, which led to this:
http://wekillbedbugs.ca/extherminate-safe-heat-kit/
Chemical-free treatment with heat. They haven't had an issue since (it has been 2 months) and the company they used offer a guarantee where they will return free of charge up to two times should they be unsuccessful.
I believe the company above is the one they went with, but there are others if you want to do your research.