Being kind of old and needing various medications, I've found unless I really needed them, I'd rather avoid the side affects some of the drugs give me. Your mileage may vary though and it's a personal decision affecting your way of life and no one other.
As for me and my pituitary gland, I've just got back some results and the doctor has raised my medication of Synthroid from 0.1mg to 0.125. mg. This I hope will help my recent lose of weight, which for me isn't good.
I know there is nothing so enthralling as listening to old farts discussing their health problems.