I put Safe N Sound between studs and in ceiling everywhere. It does some good work but will never kill all sound. You need to use sound deadening drywall screws, and the sound absorbing gyprock. I've seen where people glue double gyprock with the sound deadening glue and rubberized screws.
Sound vibrations go through studs and joists otherwise. Of course, that's all insanely expensive, so the SafeNSound at least does something., and I'm mostly happy with it. I think it cost me less than $1000 for basement and upstairs. Pick the right size of batts or you'll be cursing everything forever.
If it's a remodel, you'll be replacing most of the drywall and screws so you can maybe use the special drywall. Weigh out the cost...
There's also ventilation ductwork, especially cold air returns if you're doing this in a basement. All these things mostly prevent complete sound deadening.
Our "TV room" in basement can't hear much from outside room and can't hear stuff from room outside.
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