Have been a big fan of his standup for some time, watched all of the Lucky Louie shows and every episode of Louie, best show on TV in my opinion.
As for funniest, Amy Schumer's show gets me laughing every week. The writing is so damn good and she's just funny as hell. I've rewatched episodes multiple times.
http://en.wikipedia.org/wiki/Inside_Amy_Schumer