I'd have to beleive they are too.
When I lived at home, I had 2 (Both brother and sister) cats I had grown up with for 12 years, one day when one of them didn't come home, the other cat acted much differently for months afterwards.
He would go upstairs in the middle of the night and yowl, he gained a good deal of weight and just didn't seem right. After about 6 months of him acting like this, we got a new cat, and within a month, he was definately more like himself.
A similar thing also happened when I went to college and moved out of my parents house. For the first few weeks he'd go and urinate on various corners of my room and continue his yowling at night. It only last a few weeks since I guess he knows that I always come back at least 2x a week for various things, but there were definate changes when I did move out.
I think he was depressed/upset in both of those cases.
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