Whelp, I think the problem was in software. I ended up going into the playback mixer and easing the sliders from 100% down to 80%. My sound issues are gone and haven't come back. Can't say I understand why 100% picks up sound from monitor redraws and 80% does not, though. Sympathetic frequency?
The good news is I can turn every downstream volume control up and still get plenty of volume.
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