having seen this argument many times I only have a few points to make:
-Some fairly strong evidence exists demonstrating how chronic use does change brain physiology, especially in the developing brain. Similar things could be said for alcohol, but still should be weighed.
-The Economic benefit is not so clear cut. Many very smart people talk in circles about this, though generally it's believed to be positive.
-The savings in incarceration are definitely positive, but again the size of impact is debatable (ie, how many marijuana incarcerations have no other illegal activities involved?)
Overall, I think the case for criminalization is weak, but it's not quite clear cut. As usual, when an issue becomes trendy, emotional statements rule and the complex relationship of all things involved get ignored.
I'm for legalization, but it won't transform our lives like some advocate. I'm Dutch and have lived in Holland and yes, smoked pot there. They still have many of the same issues we deal with here, so the net positive effect is not that apparent
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