My daughter was a bit younger when we flew from London UK to Calgary and back, but these were the most helpful things for us;
I found it easier to have changing essentials in a large ziplock type bag rather than trying to have the full diaper bag in the tiny airplane toilet along with the kidlet. Put in 3 or four diapers, wipes, cream (travel size pot) and then you can just grab it and go and it doesn't take up too much room in the toilet.
Keep toys hidden that you know she likes until you leave, or buy new ones, and pack them into your carry on. Take them out one by one during the flight if she is bored and needs distraction. Of course, if she has a favourite or a stuffy that she can't sleep without, make sure you bring that.
If your wife is still breastfeeding or she is taking a bottle, try to get her to have it during take off and landings. This will encourage her to swallow and hopefully get her ears to pop and prevent them from getting too sore from the change in elevation. Might also help to comfort her, as the noise of the engines during take off may be scary for her.
They won't let you have an emergency exit row, but if you can get one behind the bulk head or any other place that might have extra leg room, take it, even if it costs a bit extra to book them. If your daughter wants to get down, it might give you some much needed extra space for her to explore without getting into other people's way.
If you can manage to get the middle seat between your wife and yourself as someone else has already suggested, for sure do that. We managed to do that on a flight with our daughter and she was able to sleep pretty well there.
The last thing that I felt helped was we took a portable dvd with us so we weren't at the mercy of the flight's entertainment system and we took dvd's that we knew she loved and could watch as much as she wanted.
That's about it. Enjoy it, and have a great time.
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