My wife used to work for Parexel, and now works for a drug company.
We were talking about this yesterday, and she wasn't too surprised, and said it happens sometimes. Of course the bizzarre side effects aren't very common though. The study she is working on right now, has had 4 deaths that were attributed to the drug (out of the 13 people in the test). I believe they were people already very sick though. She said sometimes a few people have to die to save thousands.