What exactly do you mean by slow? Is it Exchange, SQL, file/print services, or something else? Giving some more detail about the symptoms will narrow things down significantly.
If it is truly a server (not used for surfing the web and relatively immune to malware) then I would focus some energy on looking at your disks as they tend to wear out first. Maybe you have a dead/dying drive and your server is constantly trying to rebuild the raid set? Maybe you have cheap SATA disks and they can't produce enough iops to keep up?
The easiest place to start troubleshooting is event viewer as any real problems will show up in there. Feel free to post some results here as there are a ton of knowledgeable posters.
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