Quote:
Originally Posted by Flames Fan, Ph.D.
You and the poster you quoted are both actually correct. It's Ras activation that modulates PKR activity. High Ras activity, low PKR activity.
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Yes, and PKR is one of the key modules of the anti-dsRNA pathway. Thus - no PKR, dsRNA viruses replicate.
That's about the limit of my PKR knowledge - my PhD was in virology not cancer biology! Signal pathways kill my brain.