Quote:
Originally Posted by billybob123
If you're really interested, it's a protein called PKR and it's actually the opposite - PKR is sometimes shut down in cancer cells, and reovirus can only properly replicate in cells that have no PKR, so it only replicates and kills specifically PKR downregulated cells.
Now back to your regularly scheduled hockey forum.
|
You and the poster you quoted are both actually correct. It's Ras activation that modulates PKR activity. High Ras activity, low PKR activity.