Check when general sales tickets are released to the public and hit ticketmaster, could save you the stubhub premium if you time it right. I have gotten any Seahawks game that I wanted in Seattle by purchasing the day they are released.
Looks like the 49ers have released all their single game tickets already, you can check for availability at:
http://www.ticketmaster.com/San-Fran...15?list_view=1
Looks like there are still pairs available in some sections and singles available in most sections.