I had a cat die from Leukemia a few years back and your description of the symptoms sounds exactly the same as my cat had. He went from perfectly healthy to barely able to move within a few days. Very sad.
Getting a second opinion is the prudent thing to do, but if a second vet says it's Leukemia, please have the decency to put the animal out of its misery. Judging by your posts here, it sounds like you are a realistic person, but I have seen friends make very poor judgments about their pets based upon emotion alone.
I hope it works out well.
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