For parties head to Crescent street. It's usually closed off during F1 and people pack the streets everywhere around there.
You can get bottle service at pretty well any club, but except to pay twice the normal price during F1. Most of the clubs are located on St. Laurent just north of Sherbrooke.
Tonnes of great restaurants. One of the most popular in the city is Au Pied de Cochon (known for pork dishes and foie gras). I'd try to make a reservation as soon as possible if you want to eat there. L'Express is a nice French bistro, Schwartz's for smoked meat, La Banquise for poutine (especially late at night, its 24 hour), La Paryse for burgers, Fairmount or St. Viateur for bagels.
If you have any specific questions, just ask away.
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