Get him help, your parents need to know that they're having a huge influence over his self-worth, and that they need to understand that their son's well being and health, is much more important than his marks.
If you have a really open relationship with your brother, and talk to him a lot, you could also talk about how he feels quite often, and just be there as support for him, because it really sounds like your parents aren't providing much of it for him at this point. I could be wrong about your parent's effect on him, or their actions in general, and I'm sorry if I am, but this is just how I see it.
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