Dwight Freeney has a 3rd degree low basketball sprain, which is a complete tear of an ankle ligament.
http://sports.espn.go.com/nfl/playof...ory?id=4874674
It's not easy to get to Brees, unless your name is Demarcus Ware, but Freeney is the type of guy that could give Jermon Bushrod problems.
If Freeney can't go, or can't go 100% it will be a big blow to the Colts pass rush.