My seasons are in the 300's so I can give you a few tips. Its true about the bathrooms, no lineups and no waiting, especially during the period. During intermission there can be small lineups initially but it dies down around half way through. The concessions on the other hand are a nightmare. Very slow with huge lineups half way down the stairs during intermission. Sometimes during the week the lineup can be very small. For a Friday night game the lineups will be huge and slow. The food at these concessions sucks anyways so you won't be missing out on anything.
I sit on the East side of the Dome so I head to the Saddle room Restaurant between periods for beer. On the West side the they have the Alumni Lounge. If you take the first flight of stairs to the landing then head into the entrance for the suits and the elevator you will find it.
Most of the food at the Dome is horrible and overpriced. The pocket dogs are good enough but the lineup can be long. The Skyline Deli is actually pretty good, I like the BBQ pork sandwich. Lineups at the Skyline Deli and Boston Pizza go pretty fast. If you want to get a Malt during intermission wait until it is almost over as the lineups are very long. Personally I try to avoid the main concourse during intermission as it is very crowded and hard to get around.
Like other posters have mentioned don't get up during play or go back to your seat during play. Up in the 300's there are no ushers at each section to keep people from going back to their seats during play. Act like you have been to a game before and know better.
If you have time after the game go to the East side of the Dome where the players leave the parking lot. Most players will pull over to sign autographs or take pictures. I would say about 30 to 45 minutes after the game. Players will trickle out for up to 2 hours after the game. Security told me that if you want to see Kipper you need to wait till 2 hours after the game normally. If you want Brian McGratton's autograph forget about it, according to security he never stops.
Have a great time and remember to not get up during game play.
