The 101 is one of the most beautiful drives in the world, if you have the time, do it!
If you get sick and tired of windy roads and want to make up some time you can always drive inland to the I5.
Be sure to check out the Avenue of the Giants
http://www.avenueofthegiants.net/ home of the tallest trees on the planet.
Driving along the west coast of Oregon/Northern Cali is like being in the world's longest car commercial, with amazing ocean/cliff-side scenery all along the way.
Down the I5, you've got Montana (some nice mountain scenery), Idaho (yawn), Utah (not much to look at from the highway, but beautiful if you have time to explore areas like the Bryce Canyon area. Basically, it doesn't really get interesting until southern Utah or Arizona.
Are you camping? If you make it as far as central Cali, check out the Monterey area (Pebble beach road is nice), and Santa Cruz for a fun little amusement park on the beach.