Best Movie - I can't decide. Either Forrest Gump or The Shawshank Redemption.
Worst Movie - Do I have to pick one Seltzer and Friedberg movie? I mean, somehow, The Soup does a better parody of those movies than the collective hilarity of the last 5-6 movies. (Not embedded because I'm lazy and don't want to increase my post size by 100%)
http://www.youtube.com/watch?v=VpWOZmp6ajY