My advice would be to wait about 10 years before going.
Seriously, right around closing time, Disney land becomes the crakiest place on earth. You're gonna be another dad trying to carry 1 passed out toddler, while the other walks behind you crying.
This is not a comment on your child rearing ability or the general manners of your children, but trust me I'd say the VAST majority of kids leaving Disneyland do not have smiles on their faces.
For real tips though, I can say a few things regarding speed passes
1) DO NOT get a speed pass if return time is more than about 1.5 hrs away, it's a waste of a speedpass
2) DO NOT get in line for the big rides like Indiana Jones first thing in the morning (if you'll even be doing those with little kids). Grab a speed pass first thing and hit some of the smaller rides when there are no lines
3) As soon as your speed pass is ready to go (as in if it's good for 1:00 to 2:00) grab a speedpass for a second ride at about 1:01. That's the only way to overlap them and it can save a lot of time.
There's actually a website that will tell you exactly how to get the most rides in for any day, it'll actually build a schedule for you, so maybe look for that too.
Oh, and "Try the churros"
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