It'll be a little werid seeing Kelsey Grammer in a superhero role. Being a bit of a fan of Frasier (no comments please, FDW
) it'll be hard to see him in a role other then the elitist-professor like (not his role in Frasier, but the type of character he was) suit he was in Frasier. As Dr Hank McCoy, it makes sense, but when he transforms into Beast... I guess its a wait and see.
Gambit is the hero I'm really looking forward to. They hinted it in X2, so its possible.