Glove and an N95 respirator mask should take care of the odors and what not so you can do the deed.
I futzed around with Drano and various other potions to no real long lasting effect on a slow draining bathroom sink. Finally I took out the center drain stopper (a really simple thing to do) and physically removed the gunk. Jeebus. H. Chrysler. I had no idea that much tar black gunk could grow in a year and a half. A solid 1" diameter 4 plug of goo.
Or call Mike Rowe.
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