Based on the stuff I've read, serifed fonts are easier to read in print, but san serifs work better on screen. Verdana, for example, is a font that was designed for on-screen presentation (and doesn't work as well in printed form).
Times New Roman is a font that was designed to be easy to read in print (it, or some close variation, is very common in newspapers, books, and magazines). It got its name from the fact that it was designed and first used by the Times newspaper in England.
If you really want to get away from TNR, Garamond would be a good serif alternative.
If you want to go san serif, either Arial or Helvetica would be best.
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