Goto arts & crafts night at the C0ck & Bull. It's a regular pub but on Mondays or something there are free themed art supplies and you drink and make stuff...like clay, paintings, collages, puppets, etc. whatever your twisted heart desires. Good with groups with ladyfriends.
Last time I was there, this resulted from the drinks
As for clubs, depends what kind of music you like, they seemed to be quite different and changed according to the night too. Just walk up and down St. Laurent or Crescent street.